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Re: poorgradstudent post# 68740

Wednesday, 11/19/2008 6:02:01 PM

Wednesday, November 19, 2008 6:02:01 PM

Post# of 257264
I'm still trying to figure out what the overall survival was? Have I lost my id, ego, super-ego, deduction, frontal cortex, hippocampus? I've studied the GNVC pr, looked at the message boards ect... and I cannot figure it out. Too much mumbo jumbo. Didn't the FDA want or care only about overall survival? Didn't the first peak give a glimpse of something promising(first 51 patients studied at years' end '06)happening with overall survival, but not median survival at 12 months... so the FDA agreed to change the endpoint to overall survival for TNFerade. But are they saying now that overall survival was about 9.9 months in each group. Or is this the median survival. If I'm reading the data set right, the best that can be hoped for is a long slog through the entire trial. Either the PR was obtuse on purpose(or by accident); either way, it's troubling.

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