Webcast Calendar [Please see updating procedure at the end of this post. All times are U.S. ET unless indicated otherwise.] NOTE: ANYONE MAY UPDATE THIS FILE Edits: Removed obsolete entries, Added Shire, LCM, Needham, Piper Jaffray, JP Morgan Shire Analyst Day November 18, 2008 <a href="http://www.shire.com/shire/InvestorRelations/showevent.jsp?tn=2&m1=33&m2=&event=78" target="_blank">http://www.shire.com/shire/InvestorRelations/showevent.jsp?tn=2&m1=33&m2=&event=78</a> LCM 5th Annual Healthcare Conference New York, NY November 18-19, 2008 <a href="http://www.wsw.com/webcast/lz5/" target="_blank">http://www.wsw.com/webcast/lz5/</a> Needham Infectious Disease Day November 20, 2008 <a href="http://www.wsw.com/webcast/needham27/vrtx/" target="_blank">http://www.wsw.com/webcast/needham27/vrtx/</a> - Vertex <a href="http://www.wsw.com/webcast/needham28/idix/" target="_blank">http://www.wsw.com/webcast/needham28/idix/</a> - Idenix <a href="http://www.wsw.com/webcast/needham28/vphm/" target="_blank">http://www.wsw.com/webcast/needham28/vphm/</a> - ViroPharma <a href="http://www.wsw.com/webcast/needham28/ands/" target="_blank">http://www.wsw.com/webcast/needham28/ands/</a> - Anadys 20th Annual Piper Jaffray Health Care Conference in New York New York, NY December 2-3, 2008 <a href="http://www.piperjaffray.com/2col_largeright.aspx?id=1108" target="_blank">http://www.piperjaffray.com/2col_largeright.aspx?id=1108</a> 27th Annual J.P. Morgan Healthcare Conference January 12-15, 2009 -- Procedure for Updating Calendar When adding or modifying entries, please follow these steps: 1. Copy the complete text from the old calendar. 2. Make your additions or modifications, inserting new items in alphabetical or chronological order as the case may be. 3. Near the top of the message, give a very brief description of your changes (e.g. “Edits: Added JPMorgan conference”). 4. Post the updated calendar in a new message as a reply to the message with the old calendar.