Biotech Values

[DewDiligence]

Re: Xarelto quiz

>5 mg BID would provide similar plasma exposure of 10 mg QD dosing with reduced risk of bleeding.<

Exactly right. 5mg BID provides at least as great a trough exposure as 10mg qD, so the efficacy should be at least as good; moreover, 5mg BID generates a lower peak exposure than 10mg qD, so the bleeding risk ought to be less.