I think RD would be a much better target than most really tough to treat conditions or diseases-as Neuro has stated-we are pretty much the game in town versus the enormous number of players in cancer....AD...(Not that people shouldn't try to advance cancer research but it's a complete crapshoot)..I actually believe that we might really do well in AD. Plus a new drug increasing safety, I don't know -hard to reject good efficasy there. Those layoffs are long term strategic moves to ensure survival, the reverse of doing a pipe to provide cash.