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Re: zebra4o1 post# 19904

Thursday, 08/14/2008 1:14:54 PM

Thursday, August 14, 2008 1:14:54 PM

Post# of 57939
Zebra, RD-1 won't give us any useful analgesia data if -

1) The RD data is rendered useless due to 'procedural problems', as occurred in RD-2, or

2) If 1500 mg simply isn't a high enough dose to sufficiently prevent RD. It doesn't help us to see no/little change in analgesia if it's combined with no/little RD prevention.


So for the RD-1 results to be useful, we can't have procedural data 'mush', and at 1500 mg we have to see reasonably good RD prevention combined with reasonably good maintenance of analgesia.










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