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Tuesday, 07/01/2008 7:46:05 AM

Tuesday, July 01, 2008 7:46:05 AM

Post# of 252636
Something’s up at ISIS…

http://biz.yahoo.com/prnews/080701/latu035a.html

Isis Pharmaceuticals Announces a Business Update Conference Call

Tuesday July 1, 7:15 am ET

CARLSBAD, Calif., July 1 /PRNewswire-FirstCall/ -- Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ) announces the following webcast:

What: Isis Pharmaceuticals' business update

When: Tuesday, July 1, 2008, at 10:00 a.m. ET / 7:00 a.m. PT

Via internet: Simply log onto our web site http://www.isispharm.com and click on the webcast icon on our home page.

Via telephone: In the United States, call 1-877-548-7901 five to ten minutes prior to the call. You will be asked to provide your name and indicate that you wish to participate in Isis Pharmaceuticals' conference call hosted by Dr. Stanley Crooke.‹

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