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Re: rustyboy post# 11489

Thursday, 06/26/2008 7:55:56 PM

Thursday, June 26, 2008 7:55:56 PM

Post# of 19309
Re: Newfound interest in CABG indication

I’ve reread the transcripts from some of GTC’s old CC’s to get a feel for when the company’s interest in the CABG indication was reignited. Clearly, it happened during the past two years: as of Aug 2006, CABG did not even warrant a mention in the following exchange from the 2Q06 CC (#msg-12468464):

>>
Roy Friedman: [In] the U.S., at what point does GTC start thinking about an acquired-deficiency indication and is there a strong case to be made for hedging the Company's bets by selecting an indication other than DIC/sepsis?

Dr. Geoffrey Cox: Clearly, we could initiate further studies and other indications. We've talked in the past about burns, and severe burns remains an interesting area for us. I just think at this juncture we still have to be quite cautious about the cost of investment in these clinical studies, and I think certainly for the next year or so we would like to see the outcome of the DIC study before we kick off a range of other indications.

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