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Re: jessellivermore post# 11369

Saturday, 05/31/2008 7:55:44 AM

Saturday, May 31, 2008 7:55:44 AM

Post# of 19309
Dear Jesse

Actually Per.C6 (and my namesake)are perfectly capable of expressing monoclonal antibodies. In fact the press release I included in my original post which trumpeted 15gm/L is with a monoclonal antibody. I am not aware of anyone trying this cell line with plasma proteins but given the success Per.C6 has handling the complexity of a monoclonal (multiple disulfide bonds, correct folding and assembly of two seperate chains)I see no reason a priori that it can't handle these too

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