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Re: ghmm post# 60868

Tuesday, 04/01/2008 11:34:36 AM

Tuesday, April 01, 2008 11:34:36 AM

Post# of 257259
>the ITMN-191 1B trial was placebo-controlled<

But it is not blinded, which is the issue apropos to tony’s question about data availability.

>The past comments about low dose have an added clarity now that they are taking about QD potential<

I would take ITMN’s qD-dosing comments with a grain of salt insofar as there is no compelling argument I can see for qD dosing in HCV. ITMN191 will presumably be taken in a cocktail with ribavirin and a polymerase inhibitor and those drugs are dosed BID. (Note that utter dissonance with the HIV market where qD dosing is almost a necessity for commercial success.)

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