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Re: DewDiligence post# 60516

Wednesday, 03/19/2008 2:52:33 AM

Wednesday, March 19, 2008 2:52:33 AM

Post# of 257259
Size, Active-Ingredient % of Selected NNRTI’s



That Sustiva alone is almost as big as Atripla shows how challenging it must have been add Sustiva to the two other drugs in Atripla and get a pill no larger than Atripla. This was accomplished by improving the active-ingredient % from 50% to 67%.

Note: the RDEA806 pill shown above is only 200mg. In the phase-2a trial just reported, 2-4 of these pills were given simultaneously. RDEA is still working on the formulation of larger-dose pills.

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