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Tuesday, March 04, 2008 6:46:58 PM
Quiz on HIV drugs (and antivirals in general):
In the following chart (reposted from #msg-26884307),
the maximum reduction in viral load seen in selected
short-duration studies was about 2 logs (base 10).
There’s a reason none of the drugs shown above
reduced viral load by more than about 2 logs: It’s
impossible for a drug that inhibits HIV replication
to do much better than 2 logs during a one-week
study. Why is this?
In the following chart (reposted from #msg-26884307),
the maximum reduction in viral load seen in selected
short-duration studies was about 2 logs (base 10).
There’s a reason none of the drugs shown above
reduced viral load by more than about 2 logs: It’s
impossible for a drug that inhibits HIV replication
to do much better than 2 logs during a one-week
study. Why is this?
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