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Re: io_io post# 3618

Monday, 03/03/2008 8:08:23 PM

Monday, March 03, 2008 8:08:23 PM

Post# of 8473
3. Cost effects P3 trials.

Duh.

4. Clinical effect vs. stat sig

This is a point that David at BSR has been pounding the drums on. Running a 2000 patient trial to detect a microscopic improvement in some clinical condiction is just not impressive.

5. Bigger trials might be bad because safety issues could outweight benifit.

Sorry, unless I misunderstand you, you lost your mind on this one.





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