GTC Biotherapeutics (fka GTCB)

[mouton29]

I don't disagree with your basic conclusion as to the main purpose of the trial, but there does seem to be a dose-ranging aspect to the trial. That might be new, I believe that the clinicaltrials.gov entry was updated yesterday, at least the bottom of the entry says:

"ClinicalTrials.gov processed this record on February 21, 2008"

The entry now says

Official Title: Exploratory Efficacy and Safety, Pharmacokinetics and Dose Finding Study of Atryn (Antithrombin Alfa) in Patients With Disseminated Intravascular Coagulation Associated With Severe Sepsis

The summary of the clinicaltrials entry in your post of July 2007 does not mention the title, which, by the way, is the only reference to dose-finding.

I assume all this means is that they are trying different doses in the different Atryn arms. T