"I promise you the last thing these guys think about is the current stock value." Maybe not the very last thing, but still a perceptive observation if you are new at this. It's a common trait among those who run a lot of small biotech/startup pharma companies. They're science guys first and are far more interested in the laboratory than in all those pesky investors who keep inquiring about the stock. Often, they own a lot of stock themselves, but the stock price still doesn't capture a lot of their attention. In my opinion, it's just another of the tribulations of investing in this type of company.