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Re: AlpineBV_Miller post# 58147

Saturday, 01/26/2008 5:58:46 PM

Saturday, January 26, 2008 5:58:46 PM

Post# of 257257
>VRTX – It seems to me adoption would require a sig higher SVR over 12 months or at least comparable SVR over a shorter course SOC.<

Agreed that it’s a tall order. In VRTX’s favor is the fact that 72 weeks of treatment is considered the current SoC for at least part of this patient pool: the non-responders to first-line therapy. The longest Telaprevir-based arm in PROVE-3 is 48 weeks (24 weeks of T followed by 24 weeks of SoC).

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