GTC Biotherapeutics (fka GTCB)

[vinmantoo]

jesse,

I like the way you think. I was also considering that in the paper, they infused ATIII to much higher levels than normal. I am not an expert in the coagulation casacade so allow me to speculate freely. What if forcing ATIII to such high levels could trigger unintended consequences? For example, will the body react by upregulating some or all of the proteins which trigger the clotting cascade? If any of these are downstream of ATIII action, then it would bypass the effect of having the hyper levels of ATIII.