>And we're talking ORAL replacement therapy not just IV<
I wouldn’t bank on that happening in the next decade or so. Even with transgenic production, I doubt that the oral bioavailability of clotting factors will be high enough to make oral administration a practical option. After all, the point of FoB’s is to lower drug costs, not raise them.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”