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Re: ThomasS post# 6848

Wednesday, 01/09/2008 9:14:55 PM

Wednesday, January 09, 2008 9:14:55 PM

Post# of 19309
>Does anyone realistically expect the HD trial to fail?<

Failure to show non-inferior efficacy is unlikely for the reasons mentioned in #msg-25866013.

However, the trial could conceivably fail because: i) There are serious protocol violations; or ii) Some bizarre side effect shows up in a single patient in the ATryn arm.

All told, success is likely, IMO, but it cannot be taken for granted.

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