Schedule:
By the way I saw your estimate on the BV board:
AAB001- estimate 15 months enrollment + 18 month duration= 33m
==> Sept 2010 for final data
estimate interim after 9 months = Dec 2009
There is no guidance on enrollment, but I expect it will be far faster than you suggest. Unfortunately there is a limiting-step - the parallel EU trials.
One thing that I believe I know is because the "symptomatic" endopoint is usually measured at 6 months, then I would expect that is when the interim look might be.
Therefore I would expect:
aab001 - NA trials (by Elan)
=> estimate 4 months enrollment + 18 month duration = 22m
=> Oct 2009 for final data (if they open the data-box)
=> estimate interim @ 6 months = Oct 2008 (but awaits EU)
aab001 - EU trials (by Wyeth)
=> estimate start Feb '08
=> estimate 6 months enrollment + 18 month duration = 24m
=> Feb 2010 for final data
=> estimate interim after 6 months = Feb 2009
"....on the biotech battle-field, you need some élan...."