>what is the anticipated market for Atryn in the US HD indication?<
There is no formal guidance from the company. My best guess is that, within a couple of years of launch in each territory, the HD indication will produce gross annual sales of roughly $75M, of which $35M will be US, $25M EU/RoW, and $15M Japan.
Compared to the projected $1B+ of ATryn sales for the DIC indication in the US alone (#msg-19928950, #msg-22017312), you can see why it’s correct to say that HD is a small slice of the ATryn pie.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”