Gee PGS, that is a bit hard. "Companies that largely reformulate off-patent compounds aren't generally trustworthy or credible imo." I have a little cash invested in PRAN who have done just that. They have a 12 week trial on 80 alzheimers patients about to complete next month, so there are only a few months to wait for results. I think you will have to agree that if they see a strong trend to improved cognition in such a short trial, they may be credible. Yes? Although it has taken a year to enroll and complete all patients.