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Re: apljack post# 51690

Wednesday, 08/29/2007 9:18:29 PM

Wednesday, August 29, 2007 9:18:29 PM

Post# of 253325
Just offhand, I think IVIG treatment is ridiculous. All IVIG is is purified immunoglobin g. There's no selection for specificity. In other words you get a grab bag of IgG. I don't see how one can target a specific disease state, as the proportion of IgG specific to relevant epitopes is likely to be very, very low.

Unless it's used for a common disease. For example, we used to do plaque assays for herpes simplex virus by infecting the cells and covering them with media that contained purified, pooled IgG (same stuff their using in the clinic).

Plus it's hideously expensive, both to buy and to administer.

Sorry if the ridiculousness of IVIG has been covered already.
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