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DewDiligence

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DewDiligence

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Re: biopearl post# 4732

Wednesday, 08/22/2007 7:24:42 PM

Wednesday, August 22, 2007 7:24:42 PM

Post# of 19309
>If I read the previous studies re Atryn it looks like there is no effect on circulating protein C but there is with thrombomodulin. Can you help me understand how that difference might play out?<

Antithrombin inhibits a separate thrombin feedback loop from the thrombin feedback loop inhibited by thrombomodulin, which acts on protein C. Thus, it’s not a concern that antithrombin does not affect protein C—it’s not supposed to.

Let’s talk more about these technical matters after I’ve distributed the ART-123 paper. Regards, Dew

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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