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Re: OKY post# 4614

Tuesday, 08/14/2007 1:05:22 PM

Tuesday, August 14, 2007 1:05:22 PM

Post# of 19309
Might this help, OKY -

>Tangential flow filtration is an initial product recovery step that removes fats and other colloidal proteins such as casein from milk containing the target protein of interest. This approach also allows for the significant reduction in volume of the milk while yielding a material that can be aseptically processed. The resulting partially purified intermediate bulk product is more stable than unprocessed milk and can be stored for extended periods either refrigerated or frozen. The intermediate bulk product is then taken through additional purification steps, typically chromatography, to obtain a highly purified form of the desired therapeutic protein.<

http://www.transgenics.com/pressreleases/pr080105.html

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