GTC Biotherapeutics (fka GTCB)

[poorgradstudent]

Without knowing exactly how they do the purification, I can tell you that DNA is rather trivial to remove from suspensions using standard ion exchange chromatography methods.

In any case, whatever gets through will be inconsequential as humans already have some DNA circulating in their bloodstream, and there is significant DNase activity in the blood.

* DNase is the enzyme that degrades DNA. In fact, many lab purification methods will employ DNase to rid protein suspensions of DNA. In the case of GTCB, I'm not sure if they add a DNase step... it would not be how I would do it, as you would be adding a protein contaminant during the purification of another protein.