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Re: north40000 post# 50947

Sunday, 08/12/2007 2:01:12 PM

Sunday, August 12, 2007 2:01:12 PM

Post# of 257269
>> I see you noticed the marked decline in HGSI p/s over the last few weeks. Any other reason beside its investments in mortgage backed securities? <<

Yeah. There has been some concern about their best shot-on-goal, Albuferon. The drop-out rate in the P2b Albuferon trial was pretty high, there is a concern that 48 weeks treatment for genotype 1 won't be needed if any of the new HCV drugs make it to market, and there is competition coming up from behind in the once-every-two-weeks IF-alpha race.

But in my judgement, a lot of the recent drop in HGSI's stock price is probably due to those mortgage-backed securities. There are other companies with a lot of mortgage-backed securities which have suffered similarly.

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