#msg-13214528 presents a somewhat outdated overview of the HCV arena from nature.com. Since this article was written, the two main non-interferon immunomodulators (from COLY and ANDS) have been dropped, and the three main polymerase inhibitors (NM283 from NVS/IDIX, R1626 from Roche, and HCV-796 from WYE/VPHM) have run into trouble.
I guess it’s fair to say that HCV is a challenging indication for new molecular entities. Regards, Dew
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