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Re: DewDiligence post# 1464

Saturday, 08/04/2007 9:35:47 AM

Saturday, August 04, 2007 9:35:47 AM

Post# of 2446
Elbion...

With the Brookwood acquisition, SRDX acquired a Drug Delivery Partnership with elbion NV. There are two elbion products in the pipeline: elbion Naltrexone Microparticle (listed on the Brookwood website) and Buprenorphine Depot (listed on the elbion Website)

Naltrexone Depot, is a sustained release formulation of naltrexone for the treatment of alcohol (and opiate) abuse and is currently in Phase III clinical trials (I presume to meet European regulatory approval). Naltrexone Depot is designed as a once-a-month intramuscular injection which elbion believes will offer significant advantages in the treatment of alcoholism where patient treatment compliance is a major limiting factor.

Buprenorphine Depot, a sustained release buprenorphine indicated for the treatment of opiate addiction. Buprenorphine depot is in pre-clinical development.

elbion NV is a Belgian specialty pharmaceutical company formed in December, 2006 through the merger of elbion AG and 4AZA Bioscience NV. elbion AG began operations through a management buyout from Degussa Group in 2002. 4AZA was founded in 2002 as a spin-off from the Catholic University of Leuven.

Naltrexone Depot and Buprenorphine Depot were acquired in January 2007 from the French biotechnology company DrugAbuse Sciences.

Relevant Websites:
http://www.brookwoodpharma.com/pipeline.html
http://www.elbion.com/pipeline.html
http://www.elbion.com/pdf/elbion_DAS_ENG_final.pdf



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