Biotech Values

[DewDiligence]

COLY update: PF-3512676 is still breathing,
perhaps with assistance from a ventilator:

http://biz.yahoo.com/prnews/070802/neth094.html?.v=12

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“The failure of PF-3512676 in combination with cytotoxic chemotherapy to add benefit in the treatment of advanced non-small cell lung cancer was disappointing. Pfizer is continuing its trials of PF-3512676 in refractory non-small cell lung cancer in combination with Tarceva® and in advanced melanoma in combination with Pfizer's anti-CTLA-4 (cytotoxic T lymphocyte antigen-4) targeted monoclonal antibody (CP-675,206). In the coming months, we hope to provide additional clarity on Pfizer's ongoing and planned clinical programs with PF-3512676.”
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The distinguishing feature of the continuing NSCLC trial with Tarceva is that it does not include chemotherapy because Tarceva is approved as monotherapy in the second-line setting. There is no indication in COLY’s PR, however, that the PF-3512676 trial with Avastin in first-line NSCLC will go forward, nor is there any indication of a continued PF-3512676 program in breast cancer.