DNAprint Genomics (DNAG)

[johnnyfiber]

Yeah!!!! IT'S JUST LIKE THE INTERNET!!!!!LOL What's the matter? You didn't want to addess this? lol I've noticed you like to wait for the 50 post page to change...whenever your true colors have been exposed. sad...and funny...lol You're an amusing individual. lol

FROG STATED:

Furthermore your attempt to portray a 'regulatory binding site' as something outside of the protein coding process, says more about your aversion to reality than mine.

Without that site, without all other regulatory factors that are a part of the protein coding process, there would be no protein, period.

The process of creating a protein from DNA sequences is very much like the process of transferring an e-mail message over the internet. (yeah...it's just like the internet!...lol) There is the text of the message itself which is akin to the CODE, there is the Header and Footer information within the tranferred serial packets, Introns and Exons. There is formatting information hidden from the screen but essential for the correct display of the message when it reaches its target. All in all there is a great deal of information, not limited to the text itself, even though that is the main component. Nevertheless ALL OF IT is part of the coding process.

realy?....not very informed...

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I posted:


please stop embarrassing yourself...

The impact of nucleotide differences is variable and elusive, but is clearly dependent upon the location of the polymorphism in the genome. Although the majority of SNPs are likely to occur outside of actual gene encoding regions,
polymorphisms located within the context of a gene (Figure 2) need not be involved in protein encoding to result in a functional change. Nucleotide differences in regions upstream of the protein-encoding gene regions may influence the binding of promotors or repressors, resulting in differential regulation of transcription. Polymorphisms at intron/exon boundaries may effect exonic or intronic splicing enhancer or silencer positions, or especially conserved GT donor or AC acceptor positions, modifying the resulting polypeptide. There is even demonstrated potential for phenotypic effects from non-coding or synonymous SNPs through alteration of RNA secondary structure (3). Similarly, untranslated distal 3' differences may have additional effects, including interruption of poly-adenylation, which would alter the template effectiveness.

http://www.dartmouth.edu/~brenner/gene144-05/gleim.html