As for the DNA deal, I'm not as high on crystallized growth hormone working as Im on the pancreatic insufficiency indication.
Also, there's no reason why crystals could not still retain enzyme activity in their lattice form in the stomach. hGH on other hand, cant bind to its receptor in the crystalline form and you obviously dont want protein crystals circulating in your bloodstream. How exactly the hGH in the crystal is dissolved into a bioavailable monomeric form is critical here.
Your concern is more safety then actually efficacy or both? If in fact the hGH is circulating in the bloodstream would adverse events be more noticeable only in longer term usage or something that would be noticed immediately? I don't have you background in the science so just trying to get a better understanding. TIA.
Since your handle is pre-clinical I thought you'd be interested in their pre-clinical candidates as well :)
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