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Re: DewDiligence post# 48138

Wednesday, 06/06/2007 12:41:33 AM

Wednesday, June 06, 2007 12:41:33 AM

Post# of 252506
Dew,

As you know, small modifications can markedly alter the therapeutic and toxicity patterns of various chemotherapeutics. Just taking a gander at the structures says little about how similar these two agents are. Particularly because that's a fluorine--the most electronegative element--on clevudine.

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