DNAprint Genomics (DNAG)

[thesciguy]

Frog-

Do you need to learn how the genome project was accomplished?
Do you understand the process they employed?

Actually, there were two basic methods. Care to name them?

Do you realize that such a process will not uncover multiple serial copies of large DNA segments? Can you see the significance?

Neither one will. The HGP established the baseline for future comparisons to be made against it, not within it.

Do you understand how SNPs are detected?
Do you realize that a polymorphism in one segment of a CNV will trigger a positive response on a SNP array, EVEN if the SNP does not occur in the other copies? Can you see the significance?

There's that certitude again.
Not true. Period.

DO you realize that with current SNP/AIM assays, there is no way to determine whether someone has one copy of a DNA segment or ten copies? The SNP results would be the same for either case. Can you see the significance?

Seriously, are you just making this stuff up to hope that I will go away? CNVs do not invalidate correlations that may be suggested by any other method. Period. Knowledge of CNVs only increases the combined power of the analysis.

Go back and read the articles, especially the parts that explain how multiple copies of a single gene provide variable susceptibility to HIV but are 'invisible' to SNP analysis.

Cite the reference, and I'll read it. (This time, read them yourself. It's obvious to anyone who DID read the article I provided in my last post, that you simply don't know what you're talking about.)


Frog, I'm trying to help you.


Good Luck.