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Alias Born 11/15/2003

Re: DewDiligence post# 667

Friday, 12/19/2003 9:11:45 AM

Friday, December 19, 2003 9:11:45 AM

Post# of 252727
Dew, I have to think that the results for Macugen that you posted are mixed. The fact that the 90% of the patients treated with Macugen lost 6 lines, vs. 78% for the placebo, doesn't look good. On the other hand, the percentages don't add up to 100%, so I am probably misreading. (See Dew's original post for a better tabular result.)

EFFICACY
(0.3mg best dose)

Change in lines
visual acuity % of Patients
at 1 year Macugen Placebo

>=+3 (“improved”) 6 2
>= 0 33 23
> -3 (“stable”) 70 55
> -6 90 78

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