Idenix Pharmaceuticals (IDIX)

[dewophile]

thanks as always for educating me - i am really not that familiar with the replicon assay and how predictive it is of in vivo activity. On the surface it just seems that if a MOA is poorly understood, then it very well may have to do with complex interactions that a cell culture/in vitro assay just cannot predict
it seems to me ribavirin is here to stay for a while, and if nm-283 cannot be combined with ribavirin it may have limited (or no) role in upcoming HCV regimens for the forseeable future