Cytogenix (fka CYGX)

[thalio]

anti-sepsis - on the way!

http://www.quicken.com/investments/news/story/?story=NewsStory/BW/20031215/20031215005189.var&p=...

Proof of concept testing on the anti-sepsis work is about to get underway.

If the gene-silencing molecule gets into the bacteria in mice, stops them from reproducing, and lets their immune systems clear them away... we will be 99% of the way there.

This animal model of systemic infection, as far as I can see, should mimic nearly perfectly a human model. Bacteria don't reproduce any differently in the bloodstream of mice than in humans. (very young mice have immature immune systems, so if they're using them, it only means it will work more certainly in humans).

My point is, if it works here, we're more or less home free. CYGX will have to prove it to the FDA, of course (along with whatever big pharma partner is smart enough to jump onboard a new blockbuster, first-of-its-kind antibacterial)...

But WE'LL know. If it works here - it works. A new generation of gene silencing anti-bacterial that bacteria can't mutate to get around. Can't because we're attacking the very gene they need to reproduce.

TH