Advanced Micro Devices Inc (AMD)

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"if it turns out later that you might want to run some "Other" Application that you hadn't initially planned on, does that mean that maybe you're screwed? "

It sure does.
And just what IT manager wants to screw themselves by switching from Intel-based systems which have worked perfectly fine for 6 or 7 years to an AMD solution just because some AMD fan boys publishes their benchmark-flavor-of-the-month that shows some 4-way Opteron system is indeed 15% faster than a 2-way Xeon system.
Far better to go add another Xeon system than to risk bringing your entire operation to a screeching halt with a bargain-basement AMD system.
Remember - caveat emptor and "You get what you pay for"