I don't think the comments are a stretch, but there is some spin here because boger as recently as a few months ago is on record stating he thinks a shortened regimen will be 12 weeks..now while some patients may be eligible for 12 weeks of therapy based on the 6/9 svr thus far, many won't due to dropout or lack of rvr..based on an ITT remember 6/20 or 30% are thus far svr (we haven't reached the 6 month mark yet)
I think 12 triple followed by 12 soc is still looking promising..but even that is not a done deal yet...the dropout rate may seem like vrtx svr rates will be capped, but it is possible that some (even perhaps many) dropouts will still achieve svr..but if someone could only tolerate 4 weeks of vx they might have to transition to a full 48 week course of soc..so a cure might be seen in 12 weeks for a minority of patients, probably a bunch more will be ok with 24 weeks, and a not insignificant number probably will need 48 weeks based on inability to take the full prescribed regimen (in addition to those per protocol who fail to meet specified virologic endpoints), and obviously some will fail altogether
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