Biotech Values

[mouton29]

"You have two separate trials that gave conflicting outcomes on survival and TTP (or, arguably, conflicting outcomes on survival and two failures in TTP). If that doesn't need a tie-breaker, I don't know what does."

I would not call the results in the first trial (9901) "conflicting" on survival and TTP. Survival was stat sign and TTP was about .084 or .054 after some errors were corrected on audit. For want of .004 you say the null hypothesis wins? That seems awfully pedantic.

Obviously 9902A was less successful but even there it trended towards success. I agree that it is a close call whether 9902A is supportive; it was interesting that that was not discussed at the panel. But I would not go so far as to say 9902A data is conflicting.