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Re: mskatiescarletohara post# 865

Sunday, 04/15/2007 5:00:08 PM

Sunday, April 15, 2007 5:00:08 PM

Post# of 3757
>Anyone have any comments on McHutchison's comments referencing VRTX's compound. Shortening length of treatment is HUGE, quite an endorsement from McHutchison.<

I think McHutchison’s comments are good spin, but spin nonetheless.

Let me turn this issue around and ask what would happen if VX-950 were not able to shorten the SoC in HCV to 24 weeks?

Answer: it would be one of the biggest flameouts in biotech history.

Until now, the issue has been whether VX-950-based cocktails would be able to shorten SoC to twelve weeks. By touting a 24-week regimen in the VRTX PR, McHutchison is implicitly saying that the 12-week idea is dead.

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