In #msg-18783113 I said: “The fact that prior Lamivudine treatment raises resistance to Baraclude is one of the reasons that dual nucleoside treatment for HBV has not been considered a good idea.”
This applies to dual nucleoside therapy as opposed to nucleoside + nucleotide combination therapy, which is considered a promising approach, albeit one that has yet to bear fruit.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”