From Scher's letter on DNDN panel - "More important, and perhaps underappreciated during the discussion, is the recognition that the “placebo” used in this trial, a portion of the leukopheresis product that is cultured without the immunizing antigen and reinfused, may not be inert and in itself contributed to a relative worsening of survival for the control group in this tri"
I actually posted a question with regards to a possible negative placebo effect a while back before the meeting. Surprising it took so long to rear its head up. Still interested in the science and rationale behind placebo selection for different selection.