Some highlights of the studies to date pitting different chemo regimens vs. chemo plus erby:
LUCAS STUDY
Median OS tx arm=8.3 months chemo + erby Median OS control arm=7 months chemo alone
One year OS tx arm=32% One year OS control=26%
Two year OS tx arm=26% Two year OS control=0%
NOTE: all 5 patients exhibiting grade 5 rash achieved a response.
DR KELLY’S STUDY
Median survival rate of tx arm=15.7 months Control rate of tx arm=64.5%
DR. ROBERT’S STUDY
Control rate of tx arm=89%
Nsclc is a tough nut to crack. Other therapies like avastin and THI inhibitors which are approved have less efficacy and more toxicity. It seems to me (a layman of sorts) that lung has a fair chance to be approved.