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Re: rfj1862 post# 43519

Friday, 03/23/2007 6:31:44 PM

Friday, March 23, 2007 6:31:44 PM

Post# of 257259
I read that adding an ARB to an Ace Inhibitor (at the appropriate dose) doesn't increase the effect on BP on average. I will search for the article or label.

>In fact, it's been shown that when you combine various drugs that act on the renin -angiotensin system, you can get additional BP reductions. That is to say, you can put an ACE with an ARB, or a direct renin inhibitor with an ARB, and get additional BP-lowering efficacy. Why? I won't get into all the reasons for all of the steps, but one example is that there are non-ACE pathways for the conversion of angiotensin I to angiotensin II.<




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