Biotech Values

[robgera]

Why spend more money for Exforge ?

It's my understanding that both Ace Inhibitors and Angiotensin Receptor Blockers prevent or block Angiotensen II


Link: http://pecupdate.org/pecupdate/articles/ace_inhibitors_vs_angiotensin_receptor_blockers_16233.html

Excerpt: The enzyme responsible for changing angiotensin I into angiotensin II is called angiotensin-converting enzyme, or ACE. Drugs called ACE-inhibitors prevent formation of angiotensin II. So they prevent the effects of angiotensin II on blood pressure.

Link: http://www.lotrel.com/info/answers/blood_pressure_illustration.jsp

Link: http://www.aafp.org/afp/20050901/tips/10.html


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Exforge:

Diovan blocks angiotensin II, a hormone that causes blood vessels to tighten and narrow, while amlodipine blocks the entrance of calcium into the blood vessel walls. Both allow blood vessels to relax so blood can flow more easily. Exforge also provides the convenience of a single once-daily tablet, which could reduce the overall number of pills a patient may need to take.