Why else would so many people be selling their shares rather than continuing to hold?
No one -- except maybe for those in the company (and they're not talking) -- can tell you how much longer it'll be before CYGX gets the attention its technology deserves. Maybe it'll begin to come when the Chen article appears in Biotechnology in the next weeek or two; maybe it won't be until the results are released for the Herpes treatment (assuming they're as spectacular as we're all hoping); and it may be when something unexpected occurs, like a licensing or JV agreement with a major Pharma.
But I'd say if you lose faith that your patience will reap rewards, it may be time to sell.