Monday, February 02, 2026 8:21:50 PM
GERN
Stiff Competition: Rytelo struggled to gain market share against established competitors like Bristol Myers Squibb’s Reblozyl, which remains the preferred choice for many physicians due to its safety profile.
Safety and Dosing Barriers: Physicians cited concerns over cytopenia (low blood cell counts) and the inconvenience of the drug’s IV infusion requirement every four weeks as reasons for not prescribing it more broadly.
There are no issues with the OLC safety profile ...in fact it probably has fewer side effects than others like Xphozah.
OLC is a small pill ..swallowed ...its not a monthly infusion
AND ,,in TDAPA theres no prior approval hurdle . Theres no insurer saying we need you to fail on Reblozyl first before we cover GERN's drug .
AND GERN's drug has low blood cell counts ...or risk of ...and you wonder why MD's are cautious about prescribing it ?
Kiwi
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