Tornado Alley (PROG)

[fuagf]

OK, Good news. As expected, though slightly inconclusive as to exactly what it was/is, the decision is
it is not serious, in fact little more than a very bad case of eczema with tiny blisters inside the skin:

AI Overview
A severe case of eczema with tiny, fluid-filled blisters is likely dyshidrotic eczema, also known as pompholyx. This condition causes intensely itchy blisters, often described as tapioca-like, on the hands and feet. You should see a doctor for a severe or persistent rash, especially if it's painful or spreading. Treatment options include corticosteroid creams, moisture, and avoidance of triggers, but a doctor's diagnosis is necessary.
Understanding Dyshidrotic Eczema
https://www.google.com/search?client=firefox-b-d&q=very+bad+case+of+eczema%2C+with+tiny+blisters+inside+the+skin

All tests were negative for serious anomaly lol though there was one interesting result from the blood test which is fun. Leave that to the end. The final comment from the RPA Dermatology people contains much i don't understand (expected too) , but, in the interest of education, let's try to get more from it.

"The morphology of the vesicles do not lend to a single specific diagnosis." Ok, that's clear.

"There are some features that could suggest a spongiotic vesicle but usually the vesicles are less distinct, the clinical picture given is not typical and there is usually more adjacent spongiosis." Ok, what's that about:

A spongiotic vesicle is a small, fluid-filled blister that forms in the outermost layer of the skin (the epidermis) due to spongiosis, which is a type of intercellular edema or fluid accumulation between skin cells (keratinocytes). This spongiotic reaction is a key feature of eczematous dermatitis, often appearing in conditions like eczema or contact dermatitis, and results from an immune response to triggers like allergens, irritants, or even stress. Clinically, spongiotic vesicles can manifest as "juicy" papules or small, weeping blisters, and their presence indicates a severe case of eczema or another form of dermatitis.
https://www.google.com/search?client=firefox-b-d&q=spongiotic+vesicle+

Ah, so it's a medical term for a small fluid filled blister, that's easy. Next:

"There are some features of pemphigus vulgaris except for the pauciimmune morphology and lack of supportive IF.
A pauciinflammatory bullous pemphigoid should still show the characteristic linear C3 staining on IF"

LOL Bullous pemphigoid rang a bell and sure enough in our search for knowledge we had touched on that before ..
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=176594807 . The pemphigus vulgaris sounds sexy, let's see:

AI Overview
Pemphigus vulgaris is a rare, serious, and potentially life-threatening autoimmune disease causing painful blisters and sores on the skin and in mucous membranes, especially the mouth. The immune system mistakenly attacks proteins that bind skin cells, leading to cell separation and blister formation. While there is no cure, treatments like steroid tablets and other immunosuppressive medications can control the disease and promote healing, though long-term treatment is often necessary
https://www.google.com/search?client=firefox-b-d&q=pemphigus+vulgaris

Ok, like a sexy person with a genital disease, only sexy if you have nothing to do with it. Note i tentatively dismissed the prospect of that serious problem earlier in observing i had no sores in the mucous membranes. So it you ever have or hear of another who has a bad rash and those mouth sores that could indicate a serious problem.

Finally -- "Are the biopsies representative of the process? Drug induced vesicular
reaction or atopy/eczematous/irritant/allergic type bullous lesions are possible."

The nurse in the end circled from atopy above. So bottom line, as anticipated, not serious.

Re the itch she said continue the corticosteroid ointment, Eleuphrat .. https://investorshub.advfn.com/boards/read_msg.aspx?message_id=176562468 .. treatment until you don't feel any itch even beneath the skin when you lightly scratch. So ugh gotta do that. She suggested perhaps, she though, it would be another week. And she said yep continue using the huge tubs, lol , of QV Intensive once a day.

Oops almost forgot the one fun fact from one of the blood tests, the IgE test:

AI Overview
IgE Allergy Test: Purpose, Procedure And Interpretation ...
A blood IgE test measures Immunoglobulin E, a type of antibody, to help diagnose allergies, parasitic infections, or certain immune disorders. There are two main types: a total IgE test, which checks the overall level of IgE in your blood, and a specific IgE test (formerly RAST), which checks for IgE antibodies against specific allergens, such as pollen or certain foods. A positive test indicates sensitization to an allergen, but a doctor must interpret it alongside your symptoms and clinical history to confirm a diagnosis.
https://www.google.com/search?client=firefox-b-d&q=blood+IGE+test+

Umm don't know which of the two tests did but i gathered the level of the thing measured was a measure to an extent of the sensitivity of the skin. I asked what was the normal range, she said 0-100. She said mine was 1500. Yep, 1500. Just a super sensitive guy. LOL