Biotech Values

[DewDiligence]

GLP-1 side effects are sex-linked—at least in mice:

https://www.prnewswire.com/news-releases/landmark-study-explains-why-obesity-drugs-work-differently-for-women-and-men-302406164.html

The study reveals that female mice have nearly double the GLP-1 receptor expression in brain regions linked to nausea, explaining their heightened side effects. If this receptor expression pattern is consistent across species it could explain why women experience higher rates of nausea and vomiting.

… Higher estrogen levels correlate with more severe side effects, highlighting the role of hormone levels in drug response.