Summary of Amylyn/DACRA NME's in development from piper posted on X:
Nice table for a quickie summary of the Amylin assets in development - also from Piper - .. $LLY$NVO$ABBV /Gubra $ROG / $ZEAL.CO$MTSR$VKTX$GPCR - Metsera mid-yr readout for their QM Amylin asset will be an important one - VKTX / GPCR still in IND enabling stage - so data in… pic.twitter.com/zOKTXks94W
As for the difference between Amylin and DACRA's here is the response from Co-Pilot:
Dual Amylin and Calcitonin Receptor Agonists (DACRAs) and Amylin are related but distinct in their functions and applications:
DACRAs: These are a class of drugs that act as agonists at both the amylin receptor and the calcitonin receptor. They are being developed as therapies for conditions like obesity and type 2 diabetes. DACRAs combine the effects of amylin and calcitonin receptor activation, which can lead to improved glycemic control and weight loss.
Amylin: This is a naturally occurring peptide hormone co-secreted with insulin by the pancreas. It plays a role in regulating blood sugar levels by slowing gastric emptying, suppressing glucagon secretion, and promoting satiety. Amylin analogs are used in diabetes management to mimic these effects
"People are best convinced by reasons they discover themselves"